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mcpherson753

Member since: 03.15.18
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Website: https://www.abbkine.com/product/elikine-human-tgf-%CE%B21-elisa-kit-ket6030/

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TGF-beta 1 Human ELISA Kit

EliKineâ„¢ Human TGF-β1 ELISA Kit employs a two-site sandwich ELISA to quantitate Human TGF-β1.,TGFB1; CED; DPD1; LAP; TGFB; TGFbeta; TGF-beta 1 protein; latency-associated peptide,TGF-β is capable of producing a variety of effects and virtually all cell types respond to this factor in some way. The inappropriate presence of active TGF-β1 has been implicated in a variety of pathological conditions Because of the necessity for regulating its activity tightly, TGF-β is secreted by cells in the form of an inactive complex. This complex consists of TGF-β1 associated non-covalently with a protein designated the latency associated peptide (LAP). TGF-β1 and LAP represent components of a pro-peptide that is cleaved in a post-golgi compartment prior to secretion. LAP and TGF-β1 each consist of a disulfide-linked homodimer and the association of these two components renders TGF-β1 inactive and inaccessible to anti-TGF-β antibodies.

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